
Alzheimer’s Disease in Adults with Down Syndrome
Brian Chicoine, MD
October 2025
The CARE Down Syndrome Clinical Reference Articles are a growing collection of in-depth articles that offer deeper insight into key healthcare topics related to caring for individuals with Down syndrome. These articles are designed to enhance understanding and support practical application in primary care settings.

Overview of Alzheimer’s disease in adults with Down syndrome, covering earlier onset, higher risk, and both medical and non-medical management strategies.

Practical guidance for avoiding misdiagnosis by differentiating features of Down syndrome from co-occurring conditions.

Learn how to recognize common behavioral characteristics in adults with Down syndrome to avoid misdiagnosing them as psychopathology.

Review of common health conditions in adults with Down syndrome, including variations in vital signs.

Discover why decline in skills and changes in behavior are common in adults with Down syndrome, including causes, contributing factors, diagnosis, and…

Overview of Down Syndrome Regression Disorder (DSRD), a neuropsychiatric condition affecting teens and young adults with Down syndrome, including causes, evaluation, and…